DEPARTMENT OF LIPID SCIENCE
+ 91- 821-2514153 firstname.lastname@example.org
About the Department
Our main focus of research is on understanding the role of lipids in health and nutrition with an emphasis on the
most pressing current issues related to the metabolic syndrome.
This involves exploring lipid metabolism in yeast, plants and animals through biochemical, metabolomics and transcriptomic approaches. The biochemical approach consists of identification and functional characterization of genes that are involved in lipid metabolism and its regulation. In addition, application of computational methods are been carried out for gaining insights on enzyme structure-function relationships. Whereas, metabolomics investigations are aided by high resolution mass spectrometry for qualitative analysis and hybrid triple quadrupole for quantification. Transcriptomic studies mainly involve next generation sequencing or microarray analysis at the global level and specific expression analysis by quantitative PCR.
Understanding energy homeostasis and the role of gastro-intestinal peptides is an important component in our strategy for the development of probable therapeutic measures countering obesity. These studies are carried out in in vitro cell culture model using appropriate cell lines like 3T3L-1 followed by in vivo validations in rodent models. Identification of bioactives to modulate transcriptional regulation of glucose and lipid metabolism are being carried out.
Atomic and molecular level understanding of enzymatic function through advanced computational methods such as quantum /molecular mechanical studies and electronic structure studies is used as a guiding tool for manipulation and engineering of commercially important enzymes.
Development of food based bioactives and lipid based nutraceuticals for targeting life style disorders are being pursued. These nutraceuticals can be used as dietary supplements or can be included in functional foods.
Conventional breeding methods are being used for genetic improvement of plants with special focus on novel oil or lipid yielding varieties. Assessment of plant breeding is done through tissue-culture, molecular biology, analytical and biochemical techniques.